This report summary by the Colorado Department of Public Health and Environment presents the major findings from the latest data collected and scientific evidence available through 2020. The key objectives were to help facilitate evidence-based policy decisions and science-based public education in Colorado. The data that is analyzed came from validated sources and the findings are interpreted by individuals formally trained in epidemiology and biostatistics. The health statements and recommendations made were produced from the collective expertise of the Retail Marijuana Public Health Advisory Committee and were directly reflective of the science from which it came, unbiased by individual opinion. This report summary presents a condensed version of the data findings important to public health, heath statements of moderate to substantial significance, and the recommendations for continued surveillance improvement and policy influence.